TRAP (ABT522) IHC kit

    • Catalog No.:IHCM6915
    • Applications:IHC
    • Reactivity:Human;
      • Target:
      • TRAP
      • Fields:
      • >>Riboflavin metabolism;>>Metabolic pathways;>>Lysosome;>>Osteoclast differentiation;>>Rheumatoid arthritis
      • Gene Name:
      • ACP5
      • Protein Name:
      • TRAP
      • Human Gene Id:
      • 54
      • Human Swiss Prot No:
      • P13686
      • Immunogen:
      • Synthesized peptide derived from human TRAP AA range: 250-325
      • Specificity:
      • The antibody can specifically recognize human TRAP protein.
      • Source:
      • Mouse, Monoclonal/IgG1, kappa
      • Purification:
      • The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
      • Storage Stability:
      • 2°C to 8°C/1 year
      • Other Name:
      • Tartrate-resistant acid phosphatase type 5 (TR-AP;EC 3.1.3.2;Tartrate-resistant acid ATPase;TrATPase;Type 5 acid phosphatase)
      • Background:
      • This gene encodes an iron containing glycoprotein which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. [provided by RefSeq, Aug 2008],
      • Function:
      • catalytic activity:A phosphate monoester + H(2)O = an alcohol + phosphate.,cofactor:Binds 2 iron ions per subunit.,disease:This relatively minor intracellular isozyme of acid phosphatase can become the dominant isozyme in certain pathological states (Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias).,similarity:Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.,subunit:Exists either as monomer or, after proteolytic processing, as a dimer of two chains linked by disulfide bond(s).,
      • Subcellular Location:
      • Cytoplasmic
      • Expression:
      • Cytoplasmic
      • Products Images
      • Human giant cell tumor tissue was stained with Anti-TRAP (ABT522) Antibody
      • Human lung tissue was stained with Anti-TRAP (ABT522) Antibody