AMPD2 Polyclonal Antibody

    • Catalog No.:YT0212
    • Applications:WB;ELISA
    • Reactivity:Human;Mouse;Rat
      • Target:
      • AMPD2
      • Fields:
      • >>Purine metabolism;>>Metabolic pathways;>>Nucleotide metabolism
      • Gene Name:
      • AMPD2
      • Protein Name:
      • AMP deaminase 2
      • Human Gene Id:
      • 271
      • Human Swiss Prot No:
      • Q01433
      • Mouse Swiss Prot No:
      • Q9DBT5
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human AMPD2. AA range:131-180
      • Specificity:
      • AMPD2 Polyclonal Antibody detects endogenous levels of AMPD2 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • AMPD2;AMP deaminase 2;AMP deaminase isoform L
      • Observed Band(KD):
      • 100kD
      • Background:
      • The protein encoded by this gene is important in purine metabolism by converting AMP to IMP. The encoded protein, which acts as a homotetramer, is one of three AMP deaminases found in mammals. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012],
      • Function:
      • catalytic activity:AMP + H(2)O = IMP + NH(3).,function:AMP deaminase plays a critical role in energy metabolism.,pathway:Purine metabolism; IMP biosynthesis via salvage pathway; IMP from AMP: step 1/1.,similarity:Belongs to the adenosine and AMP deaminases family.,subunit:Homotetramer.,tissue specificity:Three isoforms are present in mammals: AMP deaminase 1 is the predominant form in skeletal muscle; AMP deaminase 2 predominates in smooth muscle, non-muscle tissue, embryonic muscle and undifferentiated myoblasts; AMP deaminase 3 is found in erythrocytes.,
      • Subcellular Location:
      • cytosol,
      • Expression:
      • Highly expressed in cerebellum.
      • Products Images
      • Western Blot analysis of various cells using AMPD2 Polyclonal Antibody
      • Western blot analysis of the lysates from HeLa cells using AMPD2 antibody.