• Target：
• SAPAP1

• Fields：
• >>Glutamatergic synapse

• Gene Name：
• DLGAP1

• Protein Name：
• Disks large-associated protein 1

• Human Gene Id：
• 9229

• Human Swiss Prot No：
• O14490

• Mouse Swiss Prot No：
• Q9D415

• Immunogen：
• Purified recombinant fragment of human SAPAP1 expressed in E. Coli.

• Specificity：
• SAPAP1 Monoclonal Antibody detects endogenous levels of SAPAP1 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Monoclonal, Mouse

• Dilution：
• WB 1:500 - 1:2000. IHC 1:200 - 1:1000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

• Purification：
• Affinity purification

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• DLGAP1;DAP1;GKAP;Disks large-associated protein 1;DAP-1;Guanylate kinase-associated protein;hGKAP;PSD-95/SAP90-binding protein 1;SAP90/PSD-95-associated protein 1;SAPAP1

• Molecular Weight(Da)：
• 109kD

• References：
• 1. Am J Hum Genet. 2009 Nov;85(5):628-42.
  2. Genes Immun. 2010 Apr;11(3):232-8.

• Background：
• function:Part of the postsynaptic scaffold in neuronal cells.,similarity:Belongs to the SAPAP family.,subcellular location:Found in postsynaptic density of neuronal cells.,subunit:Interacts with guanylate kinase-like domain of DLG1, DLG2, DLG3, DLG4 and AIP1. Interacts with the PDZ domain of SHANK1, SHANK2 and SHANK3. Found in a complex with DLG4 and SHANK1, SHANK2 or SHANK3. Found in a complex with DLG4 and BEGAIN. Interacts with DYL2 and LRFN1.,tissue specificity:Expressed in brain.,

• Function：
• function:Part of the postsynaptic scaffold in neuronal cells.,similarity:Belongs to the SAPAP family.,subcellular location:Found in postsynaptic density of neuronal cells.,subunit:Interacts with guanylate kinase-like domain of DLG1, DLG2, DLG3, DLG4 and AIP1. Interacts with the PDZ domain of SHANK1, SHANK2 and SHANK3. Found in a complex with DLG4 and SHANK1, SHANK2 or SHANK3. Found in a complex with DLG4 and BEGAIN. Interacts with DYL2 and LRFN1.,tissue specificity:Expressed in brain.,

• Subcellular Location：
• Cell membrane ; Peripheral membrane protein . Cell junction, synapse, postsynaptic density . Cell junction, synapse .

• Expression：
• Expressed in brain.

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